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Health Condition(s) or Problem
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Lung Cancer
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Lay Summary
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RATIONALE: Gathering information about genetic and environmental factors from patients with
lung cancer and their partners and first-degree relatives may help doctors learn more about
the disease.
PURPOSE: This clinical trial is looking at the patterns, causes, and control of disease in
patients with lung cancer in the North Trent (England) region.
(from ClinicalTrials.gov)
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Who can enter the trial
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DISEASE CHARACTERISTICS:
- Patient meeting the following criteria:
- Pathologically confirmed lung cancer or planning to undergo lung cancer surgery
pending pathological confirmation
- Evidence of active disease (i.e., not in remission)
- Meets 1 of the following criteria:
- 60 years of age and under
- Has a first-degree relative with lung cancer who is 60 years of age and
under
- Has two or more first- or second-degree relatives with lung cancer at any
age
- Control meeting the following criteria:
- Co-habiting partner of patient OR first-degree relative of patient or their
partner
- 18 years of age and over
- Resides within the North Trent Cancer Network region
PATIENT CHARACTERISTICS:
- Able and willing to complete study procedures
PRIOR CONCURRENT THERAPY:
- Not specified
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Who cannot enter the trial
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DISEASE CHARACTERISTICS:
- Patient meeting the following criteria:
- Pathologically confirmed lung cancer or planning to undergo lung cancer surgery
pending pathological confirmation
- Evidence of active disease (i.e., not in remission)
- Meets 1 of the following criteria:
- 60 years of age and under
- Has a first-degree relative with lung cancer who is 60 years of age and
under
- Has two or more first- or second-degree relatives with lung cancer at any
age
- Control meeting the following criteria:
- Co-habiting partner of patient OR first-degree relative of patient or their
partner
- 18 years of age and over
- Resides within the North Trent Cancer Network region
PATIENT CHARACTERISTICS:
- Able and willing to complete study procedures
PRIOR CONCURRENT THERAPY:
- Not specified
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What will happen
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Genetic; genetic linkage analysis; Genetic; loss of heterozygosity analysis; Genetic; mutation analysis; Genetic; polymerase chain reaction; Genetic; polymorphism analysis; Other; biologic sample preservation procedure; Other; medical chart review; Other; questionnaire administration; Procedure; evaluation of cancer risk factors
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Primary aim
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Establishment of a resource bank of high quality genomic and plasma DNA and tumor and serum samples
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Secondary Aim
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Analysis of single nucleotide polymorphisms for candidate lung cancer susceptibility genes in genomic DNA samples; No; Genetic changes of lung cancer in plasma DNA samples; No
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Participant Information Sheet
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Sorry, not currently available
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Website
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http://cancer.gov/clinicaltrials/CRC-WPH-USMS-ReSoLuCENT
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Recruitment Status
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Recruiting
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Nation
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England
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Location
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Sheffield
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