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Health Condition(s) or Problem
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Prostate Cancer
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Lay Summary
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Study of the factors that affect interest in - and uptake of - genetic testing for variants
that predispose to prostate cancer from the perspective of the patient.
(from ClinicalTrials.gov)
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Who can enter the trial
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Inclusion Criteria:
- Men with a positive family history of prostate cancer. The definition of a positive
family history will be: Men with a first degree relative with prostate cancer
diagnosed at <70 years; Men with two relatives with prostate cancer where at least on
is diagnosed at <70 years; Men with three relatives with prostate cancer diagnosed at
any age
- Age 40-69 years
- No previous biopsy for raised PSA
- Absence of any psychological, familial, sociological or geographic situation
potentially hampering compliance with the study protocol and follow-up schedule.
Exclusion Criteria:
- Previous prostate cancer
- Men from families where there is known to be a mutation in a high-risk prostate
cancer gene
- Men who have had a prostate biopsy within the last 12 months.
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Who cannot enter the trial
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Inclusion Criteria:
- Men with a positive family history of prostate cancer. The definition of a positive
family history will be: Men with a first degree relative with prostate cancer
diagnosed at <70 years; Men with two relatives with prostate cancer where at least on
is diagnosed at <70 years; Men with three relatives with prostate cancer diagnosed at
any age
- Age 40-69 years
- No previous biopsy for raised PSA
- Absence of any psychological, familial, sociological or geographic situation
potentially hampering compliance with the study protocol and follow-up schedule.
Exclusion Criteria:
- Previous prostate cancer
- Men from families where there is known to be a mutation in a high-risk prostate
cancer gene
- Men who have had a prostate biopsy within the last 12 months.
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What will happen
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Sorry, not currently available
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Primary aim
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Whether cancer worry changes between the two time-points (measured using the Impact of Event Scale)
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Secondary Aim
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Why are men interested/ not interested in seeking genetic profiling for prostate cancer, and what might be the uptake of such testing?; No; What are the expectations of this testing from the perspective of the user, what are the perceived benefits and limitations of testing and how do these change through the testing process; No; Is there a relationship between a family history of cancer, cancer worry, and a persons intention to seek genetic testing?; No; How would the information provided by such a test be used by the individual and the family and how could this impact upon the healthcare system; No
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Participant Information Sheet
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Sorry, not currently available
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Website
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Sorry, not currently available
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Recruitment Status
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Recruiting
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Nation
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England
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Location
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Sutton
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