Study of Families With Melanoma | Recruiting
Study of Families With Melanoma
Health Conditions
  • Melanoma (Skin)
Recruiting
Recruitment Status
NCT00445783
Primary Trial ID Number
Summary
RATIONALE: A study that evaluates patients' lifestyle, skin, and blood and tissue samples may help doctors understand the risk factors for melanoma relapse. PURPOSE: This clinical trial is studying the risk factors for melanoma in families with melanoma.
Primary Outcome Measures
  • Lifestyle factors governing relapse from melanoma; null; Genes governing relapse from melanoma; null; Sun exposure and genes that cause melanoma; null; Unusual moles related to sun exposure and genes that cause melanoma; null
Secondary Outcome Measures
    Sorry, this information is not available
Research Question
  • RATIONALE: A study that evaluates patients' lifestyle, skin, and blood and tissue samples may help doctors understand the risk factors for melanoma relapse. PURPOSE: This clinical trial is studying the risk factors for melanoma in families with melanoma.
Design Type
Sorry, this information is not available
Ethics Approval
Sorry, this information is not available
Publications
Sorry, this information is not available
Countries of Recruitment
United Kingdom
Participant Sex
Both
Participant Age Range
18 Years to N/A
Participant Type
Sorry, this information is not available
Trial Sample Size
3700
Participant Inclusion Criteria
  • DISEASE CHARACTERISTICS:
  • - Meets 1 of the following criteria:
  • - Newly diagnosed primary invasive melanoma (patient group)
  • - Lentigo maligna malignant melanoma allowed
  • - Rare variants of melanoma allowed, including any of the following:
  • - Acral lentiginous
  • - Subungual
  • - Ear, nose, and throat
  • - Oropharyngeal
  • - Perineal
  • - Vaginal
  • - Vulval
  • - Rectal
  • - Nodal with no known primary
  • - Patients undergoing sentinel node biopsy are eligible
  • - No in situ melanoma, melanocytic intraepidermal neoplasia, or ocular
  • melanoma
  • - Healthy participant meeting either of the following criteria (control group):
  • - Relative of a patient who was diagnosed with melanoma after September 2005
  • - Healthy volunteer who is age- and sex-matched for patients who were
  • diagnosed with melanoma before October 2005
  • PATIENT CHARACTERISTICS:
  • - Not specified
  • PRIOR CONCURRENT THERAPY:
  • - Not specified
Participant Exclusion Criteria
  • DISEASE CHARACTERISTICS:
  • - Meets 1 of the following criteria:
  • - Newly diagnosed primary invasive melanoma (patient group)
  • - Lentigo maligna malignant melanoma allowed
  • - Rare variants of melanoma allowed, including any of the following:
  • - Acral lentiginous
  • - Subungual
  • - Ear, nose, and throat
  • - Oropharyngeal
  • - Perineal
  • - Vaginal
  • - Vulval
  • - Rectal
  • - Nodal with no known primary
  • - Patients undergoing sentinel node biopsy are eligible
  • - No in situ melanoma, melanocytic intraepidermal neoplasia, or ocular
  • melanoma
  • - Healthy participant meeting either of the following criteria (control group):
  • - Relative of a patient who was diagnosed with melanoma after September 2005
  • - Healthy volunteer who is age- and sex-matched for patients who were
  • diagnosed with melanoma before October 2005
  • PATIENT CHARACTERISTICS:
  • - Not specified
  • PRIOR CONCURRENT THERAPY:
  • - Not specified
Interventions
Genetic; gene expression analysis; null; []; Genetic; mutation analysis; null; []; Other; immunohistochemistry staining method; null; []; Other; laboratory biomarker analysis; null; []; Procedure; examination; null; []; Procedure; mutation carrier screening; null; []; Procedure; study of high risk factors; null; []
Design Details
Sorry, this information is not available
Study Design
N/A
Results Reporting
Sorry, this information is not available
Acronym
Sorry, this information is not available
Scientific Title
Melanoma Family Case-Control Study Protocol
Secondary Trial Identifying Number
CDR0000532934; EU-20704
Website
Sorry, this information is not available
Study Funded By
Leeds Cancer Centre at St. James's University Hospital
Funder Type
Sorry, this information is not available
Study Sponsored By
Leeds Cancer Centre at St. James's University Hospital
Study Also Sponsored By
Sorry, this information is not available
Primary Sponsor Type
Sorry, this information is not available
Secondary Sponsor Type
Sorry, this information is not available
Key Dates

Date of First Enrollment
Date Not Available
Recruitment End Date
Date Not Available
Trial End Date
Date Not Available
Date added to Registry

07 Mar 2007

Last Updated

09 Aug 2013

Date Record Refreshed on UKCTG

31 Jul 2015