Measures of Pain Relevant to Knee Osteoarthritis | Completed
Measures of Pain Relevant to Knee Osteoarthritis

Trial Source

There is no location for this trial

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Health Conditions
  • Osteoarthritis of the Knee
Unfortunately contact details are not available for this trial.
Primary Contact Details
Completed
Recruitment Status
NCT01310257
Primary Trial ID Number
Summary
The aim is to improve understanding of the assessment of pain experience in patients with osteoarthritis (OA) of the knee. The current study will be divided into two parts. In Study 1, the investigators will analyse existing questionnaires relevant to the mechanisms and therapeutic targets of knee OA to establish discrete dimensions that discriminate between the different mechanisms of pain. On the basis of this analysis, the investigators will refine the questionnaires to maximise their sensitivity to knee OA. In Study 2, the investigators will seek to confirm the factor structure identified in the questionnaires in Study 1 and explore potential mediator and moderator variables between pain and quality of life using the refined measures. The investigators will also evaluate Quantitative Sensory Testing as a predictor of OA knee pain.
Research Details
    Sorry, this information is not available
Phase
N/A
Study Design
Observational Model: Case-Only, Time Perspective: Cross-Sectional
Study Type
Observational
Intervention
Other : Questionnaires

Study Arm Groups : Knee osteoarthritis

Intervention Type
See Interventions above
Primary Outcome Measures
  • Questionnaire set assessing physical symptoms, cognitive and emotional factors, and quality of life in knee OA.; Patients will be assessed after diagnosis of OA of the knee. There is no specific time point after diagnosis, because we are interested in a broad spectrum of patients with OA of the knee. All patients will be assessed at enrollment into the study.
Secondary Outcome Measures
  • Quantitative Sensory Testing assessing pain and sensory thresholds for a noxious stimulus (Pain Pressure Thresholds); Patients will be assessed after diagnosis of OA of the knee. There is no specific time point after diagnosis, because we are interested in a broad spectrum of patients with OA of the knee.
Publication(s)
Sorry, this information is not available
Result Reports
This is available on the Clinicaltrials.gov website
Gender
Both
Age Range
18 Years - N/A
Who Can Participate
Patients
Number of Participants
Sorry, this information is not available
Participant Inclusion Criteria
  • Inclusion Criteria:
  • - Participants in Study 1 will have OA of the knee defined and scored radiologically
  • and will report knee pain. Participants in Study 2 will also have OA of the knee, but
  • a clinical diagnosis will suffice.
  • Exclusion Criteria:
  • - Inability to speak or understand English
  • - Under the age of 18 years old
  • - knee joint surgery within three months prior to participation
  • - Diagnosed Rheumatoid Arthritis, Psoriatic Arthritis, Gout or any other inflammatory
  • arthritis disorder
  • - The participants in Study 2 will also be excluded if they participated in Study 1
Participant Exclusion Criteria
This is in the inclusion criteria above
Trial Location(s)
Nottingham
Trial Contact(s)
Primary Trial Contact
Sorry, this information is not available
Other Trial Contacts
Sorry, this information is not available
Countries Recruiting
United Kingdom
Scientific Title
Evaluation of Questionnaire Measures for Patients With Osteoarthritis of the Knee
EudraCT Number
Not available for this trial
Funder(s)
  • Arthritis Research Campaign
Other Study ID Numbers
10052
Sponsor(s)
University of Nottingham
Key Dates

Recruitment Start Date

Dec 2010

Recruitment End Date

Sep 2013

Trial Start Date
Date Not Available
Trial End Date
Date Not Available
Date Assigned

02 Mar 2011

Last Updated

16 Jan 2014