Find out about health research
Try searching for a clinical trial   You can search by condition or relevant keywords

Welcome to the UK Clinical Trials Gateway

Our site is here to help you find out about health and social care research that is taking place across the UK.

You can find out what 'clinical trials' and 'health and social care research' involves as well as finding out about studies that are happening right now into any condition or disease area.

Latest research findings

from the NIHR Dissemination Centre

A football programme for overweight men achieves sustained weight loss
A 12-week weight management programme for men, centred on football, achieved 4.9kg weight loss at 12 months. Modest weight loss of 2.9kg was maintained at 3.5 years. Rates of overweight and obesity are higher for UK men than women, and there is little evidence that interventions are effective in the longer term. This NIHR-funded study followed 488 of 747 men (65%), average age 47 years, originally allocated to a programme of behavioural advice and football training with a professional coach or to a waiting list control. In this follow-on study, the control group also received the intervention after 12 months. Improvements in self-reported physical activity and diet were also maintained. The programme was estimated to be an effective use of NHS resources. It indicates that tailored programmes can work beyond the trial setting. Evidence for what components of this programme were linked to its success could help design other interventions that don’t involve football.
16 October 2018

No benefit from monitoring antiepileptic drug levels in pregnancy
Regular monitoring of antiepileptic drug levels in pregnant women with epilepsy does not improve seizure control compared with clinical features-based monitoring. This NIHR-funded study was conducted across 50 UK hospitals and is the largest randomised trial in pregnant women with epilepsy. Just over 260 pregnant women with unstable antiepileptic drug levels were assigned to ongoing monthly blood checks or clinical features monitoring. There were no differences in seizures or other pregnancy outcomes between the two strategies. But umbilical cord blood showed that babies whose mothers received blood checks were exposed to higher levels of antiepileptic drugs. The study provides important information about the utility of monitoring blood levels of antiepileptic drugs, which previously was standard clinical practice. NICE guidelines advised against routine monitoring in 2012 and this trial gives support to this recommendation.
09 October 2018

More research news on clinical trials

Better healthcare starts with you

The UK Clinical Trials Gateway is designed to help you participate in clinical trials running in the UK.

Read more