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Welcome to the UK Clinical Trials Gateway

Our site is here to help you find out about health and social care research that is taking place across the UK.

You can find out what 'clinical trials' and 'health and social care research' involves as well as finding out about studies that are happening right now into any condition or disease area.

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Latest research findings

from the NIHR Dissemination Centre

Cognitive behavioural therapy may help ease depression in the workplace
Workplace-based interventions for people with depressive symptoms are effective. This review of 16 trials looked at early stage interventions to prevent depressive symptoms from developing into more severe depressive illness. Both cognitive behavioural therapy and some non-cognitive behavioural therapy interventions, such as supervised exercise, worked equally well. Telephone and internet-based therapy worked better than face-to-face therapy. These interventions were compared to usual treatment or being placed on a waiting list. Given the prevalence of depression in the workplace, and its high cost to productivity, these findings should be considered by employers wishing to prevent the progression of depressive symptoms in their workforce. This must include provisions to safeguard patient confidentiality and is likely to require training of managers and workplace supervisors.
12 March 2019

Treating vitamin D deficiency may reduce exacerbations of COPD
Vitamin D supplements halve the number of exacerbations of chronic obstructive pulmonary disease (COPD) in people with low levels of the vitamin, from two per year to one per year. The supplements do not affect exacerbations of COPD in people who are not deficient. This NIHR-funded review is the first to pool individual-level data from randomly controlled trials to see whether taking vitamin D can help reduce exacerbations. People with moderate to severe COPD may be at risk of low vitamin D levels because their illness reduces their opportunities to get out into the sunlight. These findings suggest that vitamin D is an effective, safe prevention for those with COPD found to be deficient.
26 February 2019

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The UK Clinical Trials Gateway is designed to help you participate in clinical trials running in the UK.

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