An Exploration of Genetic Testing for Prostate Cancer Susceptibility | Not Recruiting
An Exploration of Genetic Testing f... | Not Recruiting
An Exploration of Genetic Testing for Prostate Cancer Susceptibility

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Medical Conditions
  • Prostate Cancer
Primary Contact Details
Unfortunately contact details are not available for this trial.
Recruitment Status
Not Recruiting
Trial source and source ID number
NCT00997464

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This information is designed to help you decide whether this trial is of interest. In some cases it is provided as a link to more detailed patient information or it may still be awaited from the organisation running the trial. Please look again shortly if the information you need is not here or, if named, contact the researcher named above.
Summary
Study of the factors that affect interest in - and uptake of - genetic testing for variants that predispose to prostate cancer from the perspective of the patient.
Research Details
  • This study will use a mixed methods approach to follow men as they move through the genetic testing process, from initial contact through to receiving their genetic testing results. A questionnaire will be used to measure variables at both baseline and after proceeding through the testing process. A small cohort of men will be invited to be interviewed to gather some in depth qualitative data about the issues that have arisen during the study process.
Phase
N/A
Study Design
Observational Model: Cohort, Time Perspective: Prospective
Study Type
Observational
Intervention
Sorry, this information is not available
Intervention Type
See Interventions above
Primary Outcome Measures
    Whether cancer worry changes between the two time-points (measured using the Impact of Event Scale); null
Secondary Outcome Measures
    Why are men interested/ not interested in seeking genetic profiling for prostate cancer, and what might be the uptake of such testing?; null; What are the expectations of this testing from the perspective of the user, what are the perceived benefits and limitations of testing and how do these change through the testing process; null; Is there a relationship between a family history of cancer, cancer worry, and a persons intention to seek genetic testing?; null; How would the information provided by such a test be used by the individual and the family and how could this impact upon the healthcare system; null
Publication(s)
Sorry, this information is not available
Result Reports
Check availability of results on the Clinicaltrials.gov website
This information is designed to help you decide whether this trial is of interest. In some cases it is provided as a link to more detailed patient information or it may still be awaited from the organisation running the trial. Please look again shortly if the information you need is not here or, if named, contact the researcher named above.
Gender
Male
Age Range
40 Years - 69 Years
Who Can Participate
Sorry, this information is not available
Number of Participants
200
Participant Inclusion Criteria
    Inclusion Criteria:

    - Men with a positive family history of prostate cancer. The definition of a positive family history will be: Men with a first degree relative with prostate cancer diagnosed at <70 years; Men with two relatives with prostate cancer where at least on is diagnosed at <70 years; Men with three relatives with prostate cancer diagnosed at any age

    - Age 40-69 years

    - No previous biopsy for raised PSA

    - Absence of any psychological, familial, sociological or geographic situation potentially hampering compliance with the study protocol and follow-up schedule.

    Exclusion Criteria:

    - Previous prostate cancer

    - Men from families where there is known to be a mutation in a high-risk prostate cancer gene

    - Men who have had a prostate biopsy within the last 12 months.
Participant Exclusion Criteria
This is in the inclusion criteria above
This information is designed to help you decide whether this trial is of interest. In some cases it is provided as a link to more detailed patient information or it may still be awaited from the organisation running the trial. Please look again shortly if the information you need is not here or, if named, contact the researcher named above.
Trial Location(s)
Royal Marsden - Surrey
Sutton
England
SM2 5PT
Trial Contact(s)
Primary Trial Contact
Sorry, this information is not available
Other Trial Contacts
Sorry, this information is not available
Countries Recruiting
United Kingdom
This information is designed to help you decide whether this trial is of interest. In some cases it is provided as a link to more detailed patient information or it may still be awaited from the organisation running the trial. Please look again shortly if the information you need is not here or, if named, contact the researcher named above.
Scientific Title
An Exploration of Factors Affecting Interest and Uptake of Genetic Testing for Prostate Cancer Susceptibility: The Clinical Application of Genetic Testing for Lower Risk Cancer Predisposition Genes
EudraCT Number
Not available for this trial
Funder(s)
  • Institute of Cancer Research, United Kingdom
Other Study ID Numbers
CCR3200
Sponsor(s)
Royal Marsden NHS Foundation Trust
Key Dates

Recruitment Start Date

Aug 2009

Recruitment End Date

Feb 2011

Trial Start Date
Date Not Available
Trial End Date
Date Not Available
Date added to source

16 Oct 2009

Date updated in source

16 Oct 2009