Rubidium-82 PET and Tc-99m-MIBI SPET: A Head to Head Comparison | Completed
Rubidium-82 PET and Tc-99m-MIBI SPE... | Completed
Rubidium-82 PET and Tc-99m-MIBI SPET: A Head to Head Comparison

Trial Source

Location not identified by Google services

Location data is sourced from multiple external providers and UKCTG is not responsible for and cannot guarantee the accuracy of data.

Medical Conditions
  • Coronary Artery Disease
Unfortunately contact details are not available for this trial.
Primary Contact Details
Completed
Recruitment Status
NCT01379677
Primary Trial ID Number

We need your help to advance medical research

You can help accelerate the discovery of cures of medical conditions by signing up and creating a profile. By doing so you can register your interest in clinical trials and researchers will be able to get in touch about trials that are suitable for you.

This information is designed to help you decide whether this trial is of interest. In some cases it is provided as a link to more detailed patient information or it may still be awaited from the organisation running the trial. Please look again shortly if the information you need is not here or, if named, contact the researcher named above.
Summary
The main purpose of this study is to compare myocardial perfusion imaging using Rubidium-82 PET with Tc-99m-MIBI SPET, in the evaluation of significant Coronary Artery Disease (CAD).
Research Details
    Sorry, this information is not available
Phase
Phase 3
Study Design
Allocation: Non-Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic
Study Type
Interventional
Intervention
Drug : Rubidium-82, Drug : Sestamibi. reconstitution with sodium pertechnetate (99mTc)

Study Arm Groups : Single arm, Single arm

Intervention Type
See Interventions above
Primary Outcome Measures
    The specificity of detecting significant coronary artery disease (as defined as being >70% stenosis, on coronary CT angiography); Up to 2 days
Secondary Outcome Measures
    Evaluate any difference in the clinical interpretation of the Rubidium-82 PET and Tc-99m-MIBI SPET images.; Up to 2 days; Evaluate any difference in "Percentage myocardium" that is hypoperfused, between Rubidium-82 PET and Tc-99m-MIBI SPET.; Up to 2 days; Evaluate any difference in image quality, artefacts and interpretative confidence between Rubidium-82 PET and Tc-99m-MIBI SPET.; Up to 2 days; Evaluate any adverse events or reactions, during Rubidum-82 or Tc-MIBI administration.; Up to 2 days
Publication(s)
Sorry, this information is not available
Result Reports
Check availability of results on the Clinicaltrials.gov website
This information is designed to help you decide whether this trial is of interest. In some cases it is provided as a link to more detailed patient information or it may still be awaited from the organisation running the trial. Please look again shortly if the information you need is not here or, if named, contact the researcher named above.
Gender
Both
Age Range
40 Years - N/A
Who Can Participate
Patients
Number of Participants
Sorry, this information is not available
Participant Inclusion Criteria
    Inclusion Criteria:

    - Referred for scintigraphy to assess myocardial ischaemia

    - Ability to give informed written consent.

    Exclusion Criteria:

    - Impaired capacity to consent

    - Pregnancy, or breastfeeding

    - Allergy to iv contrast

    - Renal failure

    - Severe Uncontrolled asthma

    - Claustrophobia
Participant Exclusion Criteria
This is in the inclusion criteria above
This information is designed to help you decide whether this trial is of interest. In some cases it is provided as a link to more detailed patient information or it may still be awaited from the organisation running the trial. Please look again shortly if the information you need is not here or, if named, contact the researcher named above.
Trial Location(s)
Royal Free Hospital
London
NW1 2BU
Trial Contact(s)
Primary Trial Contact
Sorry, this information is not available
Other Trial Contacts
Sorry, this information is not available
Countries Recruiting
United Kingdom
This information is designed to help you decide whether this trial is of interest. In some cases it is provided as a link to more detailed patient information or it may still be awaited from the organisation running the trial. Please look again shortly if the information you need is not here or, if named, contact the researcher named above.
Scientific Title
Diagnosis of Coronary Artery Disease With Rubidium-82 PET and Technetium-99m-MIBI SPET: A Head to Head Comparison, Versus Coronary CT Angiography
EudraCT Number
Not available for this trial
Funder(s)
    Sorry, this information is not available
Other Study ID Numbers
2009Rb82UK
Sponsor(s)
Advanced Accelerator Applications
Key Dates

Recruitment Start Date

Feb 2011

Recruitment End Date

Nov 2013

Trial Start Date
Date Not Available
Trial End Date
Date Not Available
Date Assigned

09 Jun 2011

Last Updated

13 May 2014